服务热线
15852701687
FOXM1 Antibody
具体的参考文献 (1) RMB 1(报价是含税价格)
Description：Rabbit polyclonal antibody to FOXM1
Application：WB IHC
Reactivity：FOXM1 Antibody detects endogenous levels of total FOXM1.
Conjugate：Human, Mouse, Rat
Isotype：Rabbit
产品名称
FOXM1 Antibody
宿主
Rabbit
特异性
FOXM1 Antibody detects endogenous levels of total FOXM1.
经测试应用
适用于:WB IHC
种属反应性
与反应:Human, Mouse, Rat
预测可用于:Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
预测可用于:Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
保存
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
描述
Forkhead box M1 (FoxM1) is a forkhead box family transcription factor that regulates a number of genes throughout the cell cycle to help control DNA replication, mitosis and cell proliferation. FoxM1 expression increases during G1 and S and reaches maximum levels in G2/M . Nuclear translocation occurs just before entry into G2/M and is associated with FoxM1 phosphorylation . Phosphorylation of FoxM1 by MAPK (Ser331 Ser704), Cyclin/Cdk (Thr600, Thr611, Thr672), Plk1 (Ser715, Ser724), and Chk2 (Ser376) stabilizes and activates FoxM1 . Forkhead box M1 is expressed in all embryonic tissues but is restricted to proliferating tissues in adults . Recent studies have shown that FoxM1 expression is negatively regulated by p53 . Upregulation of FoxM1 is associated with many human cancers, including prostate, breast, lung, ovary, colon, pancreas, stomach, bladder, liver, and kidney, and may be associated with p53 mutations in some tumors . As a result, FoxM1 inhibitors have become a topic of interest for potential cancer therapy .
产品名称
FOXM1 Antibody
宿主
Rabbit
特异性
FOXM1 Antibody detects endogenous levels of total FOXM1.
经测试应用
适用于:WB IHC
种属反应性
与反应:Human, Mouse, Rat
预测可用于:Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
预测可用于:Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
保存
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
描述
Forkhead box M1 (FoxM1) is a forkhead box family transcription factor that regulates a number of genes throughout the cell cycle to help control DNA replication, mitosis and cell proliferation. FoxM1 expression increases during G1 and S and reaches maximum levels in G2/M . Nuclear translocation occurs just before entry into G2/M and is associated with FoxM1 phosphorylation . Phosphorylation of FoxM1 by MAPK (Ser331 Ser704), Cyclin/Cdk (Thr600, Thr611, Thr672), Plk1 (Ser715, Ser724), and Chk2 (Ser376) stabilizes and activates FoxM1 . Forkhead box M1 is expressed in all embryonic tissues but is restricted to proliferating tissues in adults . Recent studies have shown that FoxM1 expression is negatively regulated by p53 . Upregulation of FoxM1 is associated with many human cancers, including prostate, breast, lung, ovary, colon, pancreas, stomach, bladder, liver, and kidney, and may be associated with p53 mutations in some tumors . As a result, FoxM1 inhibitors have become a topic of interest for potential cancer therapy .
产品名称
FOXM1 Antibody
宿主
Rabbit
特异性
FOXM1 Antibody detects endogenous levels of total FOXM1.
经测试应用
适用于:WB IHC
种属反应性
与反应:Human, Mouse, Rat
预测可用于:Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
预测可用于:Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
保存
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
描述
Forkhead box M1 (FoxM1) is a forkhead box family transcription factor that regulates a number of genes throughout the cell cycle to help control DNA replication, mitosis and cell proliferation. FoxM1 expression increases during G1 and S and reaches maximum levels in G2/M . Nuclear translocation occurs just before entry into G2/M and is associated with FoxM1 phosphorylation . Phosphorylation of FoxM1 by MAPK (Ser331 Ser704), Cyclin/Cdk (Thr600, Thr611, Thr672), Plk1 (Ser715, Ser724), and Chk2 (Ser376) stabilizes and activates FoxM1 . Forkhead box M1 is expressed in all embryonic tissues but is restricted to proliferating tissues in adults . Recent studies have shown that FoxM1 expression is negatively regulated by p53 . Upregulation of FoxM1 is associated with many human cancers, including prostate, breast, lung, ovary, colon, pancreas, stomach, bladder, liver, and kidney, and may be associated with p53 mutations in some tumors . As a result, FoxM1 inhibitors have become a topic of interest for potential cancer therapy .
产品名称
FOXM1 Antibody
宿主
Rabbit
特异性
FOXM1 Antibody detects endogenous levels of total FOXM1.
经测试应用
适用于:WB IHC
种属反应性
与反应:Human, Mouse, Rat
预测可用于:Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
预测可用于:Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
保存
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
描述
Forkhead box M1 (FoxM1) is a forkhead box family transcription factor that regulates a number of genes throughout the cell cycle to help control DNA replication, mitosis and cell proliferation. FoxM1 expression increases during G1 and S and reaches maximum levels in G2/M . Nuclear translocation occurs just before entry into G2/M and is associated with FoxM1 phosphorylation . Phosphorylation of FoxM1 by MAPK (Ser331 Ser704), Cyclin/Cdk (Thr600, Thr611, Thr672), Plk1 (Ser715, Ser724), and Chk2 (Ser376) stabilizes and activates FoxM1 . Forkhead box M1 is expressed in all embryonic tissues but is restricted to proliferating tissues in adults . Recent studies have shown that FoxM1 expression is negatively regulated by p53 . Upregulation of FoxM1 is associated with many human cancers, including prostate, breast, lung, ovary, colon, pancreas, stomach, bladder, liver, and kidney, and may be associated with p53 mutations in some tumors . As a result, FoxM1 inhibitors have become a topic of interest for potential cancer therapy .
产品名称
FOXM1 Antibody
宿主
Rabbit
特异性
FOXM1 Antibody detects endogenous levels of total FOXM1.
经测试应用
适用于:WB IHC
种属反应性
与反应:Human, Mouse, Rat
预测可用于:Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
预测可用于:Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
保存
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
描述
Forkhead box M1 (FoxM1) is a forkhead box family transcription factor that regulates a number of genes throughout the cell cycle to help control DNA replication, mitosis and cell proliferation. FoxM1 expression increases during G1 and S and reaches maximum levels in G2/M . Nuclear translocation occurs just before entry into G2/M and is associated with FoxM1 phosphorylation . Phosphorylation of FoxM1 by MAPK (Ser331 Ser704), Cyclin/Cdk (Thr600, Thr611, Thr672), Plk1 (Ser715, Ser724), and Chk2 (Ser376) stabilizes and activates FoxM1 . Forkhead box M1 is expressed in all embryonic tissues but is restricted to proliferating tissues in adults . Recent studies have shown that FoxM1 expression is negatively regulated by p53 . Upregulation of FoxM1 is associated with many human cancers, including prostate, breast, lung, ovary, colon, pancreas, stomach, bladder, liver, and kidney, and may be associated with p53 mutations in some tumors . As a result, FoxM1 inhibitors have become a topic of interest for potential cancer therapy .
